WDR77 antibody

Catalog No. ABIN7251997

Product Details anti-WDR77 Antibody

Target: WDR77 (WD Repeat Domain 77 (WDR77))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This WDR77 antibody is un-conjugated

Application: ELISA, Western Blotting (WB)

Characteristics: Polyclonal Antibody

Purification: Antigen affinity purification

Immunogen: Fusion protein of human WDR77

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000, ELISA 1:2000-1:5000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for WDR77

Target: WDR77 (WD Repeat Domain 77 (WDR77))

Alternative Name: WDR77 (WDR77 Products)

Synonyms: MEP-50 antibody, MEP50 antibody, Nbla10071 antibody, RP11-552M11.3 antibody, p44 antibody, p44/Mep50 antibody, 2610003I18Rik antibody, 2610312E17Rik antibody, C79984 antibody, p44/MEP50 antibody, RGD1310479 antibody, mep50 antibody, valois antibody, WDR77 antibody, zgc:65780 antibody, zgc:77274 antibody, WD repeat domain 77 antibody, WD repeat domain 77 S homeolog antibody, WDR77 antibody, Wdr77 antibody, wdr77.S antibody, wdr77 antibody

Background: WDR77 is a component of the 20S PRMT5 (MIM 604045)-containing methyltransferase complex, which modifies specific arginines to dimethylarginines in several spliceosomal Sm proteins (see MIM 601061). This modification targets Sm proteins to the survival of motor neurons (SMN) complex (see MIM 600354) for assembly into small nuclear ribonucleoprotein core particles (Friesen et al., 2002 [PubMed 11756452]).

Molecular Weight:

Observed_MW: Refer to figures

Calculated_MW: 37 kDa

UniProt: Q9BQA1

Pathways: Ribonucleoprotein Complex Subunit Organization