The Rabbit Polyclonal anti-INCENP antibody (ABIN6241681) specifically detects INCENP in WB.
The antibody is reactive with Human, Rat and Mouse samples.
INCENP
(Inner Centromere Protein Antigens 135/155kDa (INCENP))
Alternative Name
INCENP
Background
Component of the chromosomal passenger complex (CPC), a complex that acts as a key regulator of mitosis. The CPC complex has essential functions at the centromere in ensuring correct chromosome alignment and segregation and is required for chromatin-induced microtubule stabilization and spindle assembly. Probably acts through association with AURKB or AURKC. Seems to bind directly to microtubules. Controls the kinetochore localization of BUB1.