DLL4 antibody
Quick Overview for DLL4 antibody (ABIN6242278)
Target
See all DLL4 AntibodiesReactivity
Host
Clonality
Conjugate
Application
Clone
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Predicted Reactivity
- H
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Purification
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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Immunogen
- This DLL4 antibody is generated from a rabbit immunized with a recombinant protein from the human region of human DLL4.
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Isotype
- Ig Fraction
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Application Notes
- WB: 1:2000
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- 4 °C,-20 °C
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Expiry Date
- 6 months
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- DLL4 (delta-Like 4 (DLL4))
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Alternative Name
- DLL4
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Background
- Involved in the Notch signaling pathway as Notch ligand. Activates NOTCH1 and NOTCH4. Involved in angiogenesis, negatively regulates endothelial cell proliferation and migration and angiogenic sprouting. Essential for retinal progenitor proliferation is required for suppressing rod fates in late retinal progenitors as well as for proper generation of other retinal cell types. During spinal cord neurogenesis, inhibits V2a interneuron fate.
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Molecular Weight
- 74605
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UniProt
- Q9NR61
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Pathways
- Notch Signaling
Target
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