PRDM16 antibody (AA 779-996)
Quick Overview for PRDM16 antibody (AA 779-996) (ABIN6242534)
Target
See all PRDM16 AntibodiesReactivity
Host
Clonality
Conjugate
Application
Clone
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Binding Specificity
- AA 779-996
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Purification
- This antibody is purified through a protein G column, followed by dialysis against PBS.
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Immunogen
- This PRDM16 antibody is generated from a mouse immunized with a recombinant protein between 779-996 amino acids from PRDM16.
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Isotype
- IgG1 kappa
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Application Notes
- WB: 1:4000
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Purified monoclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- 4 °C,-20 °C
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Expiry Date
- 6 months
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- PRDM16 (PR Domain Containing 16 (PRDM16))
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Alternative Name
- PRDM16
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Background
- Binds DNA and functions as a transcriptional regulator. Functions in the differentiation of brown adipose tissue (BAT) which is specialized in dissipating chemical energy in the form of heat in response to cold or excess feeding while white adipose tissue (WAT) is specialized in the storage of excess energy and the control of systemic metabolism. Together with CEBPB, regulates the differentiation of myoblastic precursors into brown adipose cells. Functions also as a repressor of TGF-beta signaling. Isoform 4 may regulate granulocytes differentiation.
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Molecular Weight
- 140251
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UniProt
- Q9HAZ2
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Pathways
- Stem Cell Maintenance, Brown Fat Cell Differentiation
Target
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