RAD51 antibody (AA 1-339)
Quick Overview for RAD51 antibody (AA 1-339) (ABIN6242792)
Target
See all RAD51 AntibodiesReactivity
Host
Clonality
Conjugate
Application
Clone
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Binding Specificity
- AA 1-339
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Purification
- This antibody is purified through a protein G column, followed by dialysis against PBS.
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Immunogen
- This RAD51 antibody is generated from a mouse immunized with a recombinant protein between 1-339 amino acids from human RAD51.
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Isotype
- IgG2b kappa
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Application Notes
- WB: 1:4000
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Purified monoclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- 4 °C,-20 °C
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Expiry Date
- 6 months
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- RAD51 (DNA Repair Protein Homolog 1 (RAD51))
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Alternative Name
- RAD51
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Background
- Participates in a common DNA damage response pathway associated with the activation of homologous recombination and double-strand break repair. Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Underwinds duplex DNA and forms helical nucleoprotein filaments. Part of a PALB2- scaffolded HR complex containing BRCA2 and RAD51C and which is thought to play a role in DNA repair by HR. Plays a role in regulating mitochondrial DNA copy number under conditions of oxidative stress in the presence of RAD51C and XRCC3.
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Molecular Weight
- 36966
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UniProt
- Q06609
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Pathways
- DNA Damage Repair
Target
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