Endoglin antibody (C-Term)
Quick Overview for Endoglin antibody (C-Term) (ABIN6242845)
Target
See all Endoglin (ENG) AntibodiesReactivity
Host
Clonality
Conjugate
Application
Clone
-
-
Binding Specificity
- AA 554-587, C-Term
-
Purification
- This antibody is purified through a protein A column, followed by peptide affinity purification.
-
Immunogen
- This ENG antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 554-587 amino acids from the C-terminal region of human ENG.
-
Isotype
- Ig Fraction
-
-
-
-
Application Notes
- WB: 1:1000
-
Restrictions
- For Research Use only
-
-
-
Format
- Liquid
-
Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
-
Preservative
- Sodium azide
-
Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Storage
- 4 °C,-20 °C
-
Expiry Date
- 6 months
-
-
- Endoglin (ENG)
-
Alternative Name
- ENG
-
Background
- Major glycoprotein of vascular endothelium. Involved in the regulation of angiogenesis. May play a critical role in the binding of endothelial cells to integrins and/or other RGD receptors. Acts as TGF-beta coreceptor and is involved in the TGF- beta/BMP signaling cascade. Required for GDF2/BMP9 signaling through SMAD1 in endothelial cells and modulates TGF-beta1 signaling through SMAD3.
-
Molecular Weight
- 70578
-
UniProt
- P17813
Target
-