Dihydrofolate Reductase antibody (N-Term)

Catalog No. ABIN6242878

The Rabbit Polyclonal anti-Dihydrofolate Reductase antibody (Clone RB49346) (ABIN6242878) specifically detects Dihydrofolate Reductase in WB and IHC (p). The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for Dihydrofolate Reductase antibody (N-Term) (ABIN6242878)

Target: Dihydrofolate Reductase (DHFR)

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Dihydrofolate Reductase antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: RB49346

Product Details anti-Dihydrofolate Reductase Antibody

Binding Specificity: AA 16-30, N-Term

Predicted Reactivity: B, Pig

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This DHFR antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 16-30 amino acids from the N-terminal region of human DHFR.

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000. IHC-P: 1:25. IHC-P: 1:25

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Expiry Date: 6 months

Target Details for Dihydrofolate Reductase

Target: Dihydrofolate Reductase (DHFR)

Alternative Name: DHFR

Background: Key enzyme in folate metabolism. Contributes to the de novo mitochondrial thymidylate biosynthesis pathway. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. Binds its own mRNA and that of DHFRL1.

Molecular Weight: 21453

UniProt: P00374

Pathways: Mitotic G1-G1/S Phases