USP47 antibody (C-Term)

Catalog No. ABIN7454387

The Rabbit Polyclonal anti-USP47 antibody (ABIN7454387) specifically detects USP47 in IP and IHC (fp). The antibody is reactive with Human samples.

Quick Overview for USP47 antibody (C-Term) (ABIN7454387)

Target: USP47 (Ubiquitin Specific Peptidase 47 (USP47))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This USP47 antibody is un-conjugated

Application: Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Product Details anti-USP47 Antibody

Binding Specificity: C-Term

Purpose: Rabbit anti-USP47 Antibody, Affinity Purified

Predicted Reactivity: Chicken

Purification: Affinity Purified

Immunogen: between AA 1237 and C-term

Isotype: IgG

Application Details

Application Notes:

IHC: 1:500 - 1:2,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

IP: 2 - 5 μg/mg lysate

WB: Not recommended. Use rabbit anti-USP47 antibody A301-048A.

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for USP47

Target: USP47 (Ubiquitin Specific Peptidase 47 (USP47))

Alternative Name: USP47

Background: Background: Ubiquitin (Ub) is a highly conserved protein found ubiquitously in eukaryotic organisms. The conjugation of ubiquitin to proteins is an important means to regulate protein activity for many cellular processes by tagging them for degradation. Removal of Ub can rescue proteins from degradation. This is accomplished by the ubiquitin-specific processing protease (UBP) family of enzymes. Ubiquitin specific peptidase (USP47) is a UBP.

Gene ID: 55031

NCBI Accession: NP_060414

UniProt: Q96K76

Pathways: Negative Regulation of intrinsic apoptotic Signaling