MAPK12 antibody (AA 319-353)

Catalog No. ABIN6243201

The Rabbit Polyclonal anti-MAPK12 antibody is suitable to detect MAPK12 in samples from Zebrafish (Danio rerio). It has been validated for WB.

Quick Overview for MAPK12 antibody (AA 319-353) (ABIN6243201)

Target: MAPK12 (Mitogen-Activated Protein Kinase 12 (MAPK12))

Reactivity: Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MAPK12 antibody is un-conjugated

Application: Western Blotting (WB)

Clone: RB47232

Product Details anti-MAPK12 Antibody

Binding Specificity: AA 319-353

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This (DANRE) mapk12 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 319-353 amino acids of DANRE mapk12.

Isotype: IgG

Application Details

Application Notes: WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Expiry Date: 6 months

Target Details for MAPK12

Target: MAPK12 (Mitogen-Activated Protein Kinase 12 (MAPK12))

Alternative Name: mapk12

Background: Serine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway. MAPK12 is one of the four p38 MAPKs which play an important role in the cascades of cellular responses evoked by extracellular stimuli such as proinflammatory cytokines or physical stress leading to direct activation of transcription factors. Accordingly, p38 MAPKs phosphorylate a broad range of proteins and it has been estimated that they may have approximately 200 to 300 substrates each. Some of the targets are downstream kinases such as MAPKAPK2, which are activated through phosphorylation and further phosphorylate additional targets (By similarity).

Molecular Weight: 41971

UniProt: O42376

Pathways: MAPK Signaling, Neurotrophin Signaling Pathway, Regulation of Muscle Cell Differentiation, Hepatitis C, BCR Signaling, S100 Proteins