MEK2 antibody (AA 204-233)

Catalog No. ABIN6243253

The Rabbit Polyclonal anti-MEK2 antibody (Clone RB12777) (ABIN6243253) specifically detects MEK2 in WB. The antibody is reactive with Human samples.

Quick Overview for MEK2 antibody (AA 204-233) (ABIN6243253)

Target: MEK2 (MAP2K2) (Mitogen-Activated Protein Kinase Kinase 2 (MAP2K2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MEK2 antibody is un-conjugated

Application: Western Blotting (WB)

Clone: RB12777

Product Details anti-MEK2 Antibody

Binding Specificity: AA 204-233

Predicted Reactivity: D, E, Ha, M, Rb, Rat, X, C

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This MAP2K2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 204-233 amino acids from human MAP2K2.

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Expiry Date: 6 months

Target Details for MEK2

Target: MEK2 (MAP2K2) (Mitogen-Activated Protein Kinase Kinase 2 (MAP2K2))

Alternative Name: MAP2K2

Background: MAP2K2 is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase is known to play a critical role in mitogen growth factor signal transduction. It phosphorylates and thus activates MAPK1/ERK2 and MAPK2/ERK3. The activation of this kinase itself is dependent on the Ser/Thr phosphorylation by MAP kinase kinase kinases. The inhibition or degradation of this kinase is found to be involved in the pathogenesis of Yersinia and anthrax.

Molecular Weight: 44424

NCBI Accession: NP_109587

UniProt: P36507

Pathways: MAPK Signaling, RTK Signaling, Fc-epsilon Receptor Signaling Pathway, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Toll-Like Receptors Cascades, Signaling of Hepatocyte Growth Factor Receptor, BCR Signaling