RYK antibody (AA 260-565)

Catalog No. ABIN6243294

The Mouse Monoclonal anti-RYK antibody is suitable to detect RYK in samples from Human. It has been validated for WB and FACS.

Quick Overview for RYK antibody (AA 260-565) (ABIN6243294)

Target: RYK (RYK Receptor-Like Tyrosine Kinase (RYK))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This RYK antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS)

Clone: 1671CT575-42-61

Product Details anti-RYK Antibody

Binding Specificity: AA 260-565

Purification: This antibody is purified through a protein G column, followed by dialysis against PBS.

Immunogen: This RYK antibody is generated from a mouse immunized with a KLH conjugated synthetic peptide between 260-565 amino acids from human RYK.

Isotype: IgG1 kappa

Application Details

Application Notes: WB: 1:1000. FC: 1:25

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified monoclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Expiry Date: 6 months

Target Details for RYK

Target: RYK (RYK Receptor-Like Tyrosine Kinase (RYK))

Alternative Name: RYK

Background: May be a coreceptor along with FZD8 of Wnt proteins, such as WNT1, WNT3, WNT3A and WNT5A. Involved in neuron differentiation, axon guidance, corpus callosum establishment and neurite outgrowth. In response to WNT3 stimulation, receptor C- terminal cleavage occurs in its transmembrane region and allows the C-terminal intracellular product to translocate from the cytoplasm to the nucleus where it plays a crucial role in neuronal development.

Molecular Weight: 67815

UniProt: P34925

Pathways: RTK Signaling, WNT Signaling, Regulation of Cell Size