GAPDHS antibody (AA 104-134)

Catalog No. ABIN6243346

Product Details anti-GAPDHS Antibody

Target: GAPDHS (Glyceraldehyde-3-Phosphate Dehydrogenase, Spermatogenic (GAPDHS))

Binding Specificity: AA 104-134

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GAPDHS antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

Predicted Reactivity: Pr

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen: This GAPDHS antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 104-134 amino acids from the Central region of human GAPDHS.

Clone: RB16542

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000. IHC-P: 1:50~100. FC: 1:10~50

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Expiry Date: 6 months

References for anti-GAPDHS antibody (ABIN6243346)

Maselli, Hales, Robaire: "The effects of chemotherapy with bleomycin, etoposide, and cis-platinum (BEP) on rat sperm chromatin remodeling, fecundity and testicular gene expression in the progeny." in: Biology of reproduction, Vol. 89, Issue 4, pp. 85, (2014) (PubMed).

Maselli, Hales, Chan, Robaire: "Exposure to bleomycin, etoposide, and cis-platinum alters rat sperm chromatin integrity and sperm head protein profile." in: Biology of reproduction, Vol. 86, Issue 5, pp. 166, 1-10, (2012) (PubMed).

Target Details for GAPDHS

Target: GAPDHS (Glyceraldehyde-3-Phosphate Dehydrogenase, Spermatogenic (GAPDHS))

Alternative Name: GAPDHS (GAPDHS Products)

Synonyms: GAPDS antibody, GAPDHS antibody, GAPD2 antibody, GAPDH-2 antibody, HSD-35 antibody, Gapd-s antibody, Gapds antibody, gapdh-2 antibody, cb350 antibody, fb71f08 antibody, fk58c09 antibody, g3pdh antibody, gapdh antibody, gapds antibody, wu:fb71f08 antibody, wu:fk58c09 antibody, zgc:76908 antibody, glyceraldehyde-3-phosphate dehydrogenase, spermatogenic antibody, GAPDHS antibody, Gapdhs antibody, gapdhs antibody

Background: GAPDHS is a protein belonging to the glyceraldehyde-3-phosphate dehydrogenase family of enzymes that play an important role in carbohydrate metabolism. Like its somatic cell counterpart, this sperm-specific enzyme functions in a nicotinamide adenine dinucleotide-dependent manner to remove hydrogen and add phosphate to glyceraldehyde 3-phosphate to form 1,3-diphosphoglycerate. During spermiogenesis, this enzyme may play an important role in regulating the switch between different energy-producing pathways, and it is required for sperm motility and male fertility.

Molecular Weight: 44501

NCBI Accession: NP_055179

UniProt: O14556

Pathways: Regulation of Carbohydrate Metabolic Process