PAX6 antibody (AA 183-214)

Catalog No. ABIN6243940

This anti-PAX6 antibody is a Rabbit Polyclonal antibody detecting PAX6 in WB. Suitable for Human.

Quick Overview for PAX6 antibody (AA 183-214) (ABIN6243940)

Target: PAX6 (Paired Box 6 (PAX6))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PAX6 antibody is un-conjugated

Application: Western Blotting (WB)

Clone: RB51294

Product Details anti-PAX6 Antibody

Binding Specificity: AA 183-214

Predicted Reactivity: B, Zf, M

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This PAX6 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 183-214 amino acids from the Central region of human PAX6.

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Expiry Date: 6 months

Target Details for PAX6

Target: PAX6 (Paired Box 6 (PAX6))

Alternative Name: PAX6

Background: Transcription factor with important functions in the development of the eye, nose, central nervous system and pancreas. Required for the differentiation of pancreatic islet alpha cells (By similarity). Competes with PAX4 in binding to a common element in the glucagon, insulin and somatostatin promoters. Regulates specification of the ventral neuron subtypes by establishing the correct progenitor domains (By similarity). Isoform 5a appears to function as a molecular switch that specifies target genes.

Molecular Weight: 46683

UniProt: P26367

Pathways: Peptide Hormone Metabolism, Carbohydrate Homeostasis