SRRT antibody (AA 878-910)

Catalog No. ABIN6244192

Product Details anti-SRRT Antibody

Target: SRRT (Serrate RNA Effector Molecule Homolog (SRRT))

Binding Specificity: AA 878-910

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SRRT antibody is un-conjugated

Application: Western Blotting (WB)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This DANRE srrt antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 878-910 amino acids from DANRE srrt.

Clone: RB53166

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Expiry Date: 6 months

Target Details for SRRT

Target: SRRT (Serrate RNA Effector Molecule Homolog (SRRT))

Alternative Name: srrt (SRRT Products)

Background: Acts as a mediator between the cap-binding complex (CBC) and the primary microRNAs (miRNAs) processing machinery during cell proliferation. Contributes to the stability and delivery of capped primary miRNA transcripts to the primary miRNA processing complex, thereby playing a role in RNA-mediated gene silencing (RNAi) by miRNAs (By similarity). Independently of its activity on miRNAs, necessary and sufficient to promote neural stem cell self- renewal. Does so by directly binding SOX2 promoter and positively regulating its transcription (By similarity).

Molecular Weight: 103274

UniProt: Q66I22

Pathways: Notch Signaling, Stem Cell Maintenance