Uroplakin 3A antibody (AA 260-279)

Catalog No. ABIN6252154

The Rabbit Polyclonal anti-Uroplakin 3A antibody is suitable to detect Uroplakin 3A in samples from Human. It has been validated for WB, FACS and IF.

Quick Overview for Uroplakin 3A antibody (AA 260-279) (ABIN6252154)

Target: Uroplakin 3A (UPK3A)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Uroplakin 3A antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (IF)

Product Details anti-Uroplakin 3A Antibody

Binding Specificity: AA 260-279

Purification: Protein A affinity chromatography

Immunogen: A synthetic peptide, aa 260-279 (GASESSYTSVNRGPPLDRAE) of human Uroplakin 3A was used as the immunogen for this antibody.

Isotype: IgG

Application Details

Application Notes: Flow Cytometry: 0.5-1 μg/million cells

IF: 1-2 μg/mL

WB: 0.5-1 μg/mL

The concentration stated for each application is a general starting point. Variations in protocols, secondaries and substrates may require the antibody to be titered up or down for optimal performance.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: PBS with 0.1 mg/mL BSA and 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot and Store at -20C. Avoid freez-thaw cycles.

Target Details for Uroplakin 3A

Target: Uroplakin 3A (UPK3A)

Alternative Name: Uroplakin 3A

Background: Uroplakin 3A (UPK3A) is a component of the asymmetric unit membrane (AUM). It is a highly specialized bio-membrane made by terminally differentiated urothelial cells. Uroplakin 3A may play an important role in AUM-cytoskeleton interaction in terminally differentiated urothelial cells. It also contributes to the formation of urothelial glycocalyx, which may play an important role in preventing bacterial adherence through FimH bacterial protein binding leading to bladder infection. Uroplakin 3A has been shown as a helpful marker for the detection of bladder cancer.

Gene ID: 7380

UniProt: O75631