MAPKAP1 antibody (C-Term)
Quick Overview for MAPKAP1 antibody (C-Term) (ABIN6252515)
Target
See all MAPKAP1 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- C-Term
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Purification
- Protein A purified antibody
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Immunogen
- A recombinant protein fragment from the C-terminal region of human SIN1 was used as the immunogen for this antibody.
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Isotype
- IgG
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anti-Mitogen-Activated Protein Kinase Associated Protein 1 (MAPKAP1) (AA 8-236) antibody
MAPKAP1 Reactivity: Human WB, IHC, IP, ICC Host: Rabbit Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase Associated Protein 1 (MAPKAP1) (AA 370-486) antibodyMAPKAP1 Reactivity: Human WB, IHC Host: Rabbit Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase Associated Protein 1 (MAPKAP1) (AA 100-150) antibodyMAPKAP1 Reactivity: Human, Mouse, Rat, Dog, Cow WB, IHC, IHC (p) Host: Rabbit Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase Associated Protein 1 (MAPKAP1) (AA 1-290) antibodyMAPKAP1 Reactivity: Human WB, ELISA Host: Rabbit Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase Associated Protein 1 (MAPKAP1) (AA 85-102) antibodyMAPKAP1 Reactivity: Human, Mouse, Rat, Dog, Cow, Chicken, Horse, Sheep, Bat, Monkey, Rabbit, Zebrafish (Danio rerio) WB Host: Rabbit Polyclonal unconjugated
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Application Notes
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Western blot: 1-3 μg/mL
Provided assay concentrations are suggestions only, SIN1 antibody titration may be required for optimal results. -
Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.5 mg/mL
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Buffer
- PBS with 0.1 mg/mL BSA and 0.05 % sodium azide
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- Aliquot and Store at -20C. Avoid freez-thaw cycles.
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- MAPKAP1 (Mitogen-Activated Protein Kinase Associated Protein 1 (MAPKAP1))
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Alternative Name
- SIN1
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Background
- MTOR, or Mammalian target of rapamycin, a large protein kinase, is a regulator of cell growth and survival via its mTORC1 (mTOR + GBL + Raptor) and mTORC2 (mTOR + GBL + SIN1 + Rictor) complexes. SIN1 is an essential component of mTORC2, which activates Akt by phosphorylating Ser473. Phosphorylation of SIN1 at Thr86/398 causes its dissociation from the mTORC2 complex, inhibiting mTORC2s kinase activity.
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Gene ID
- 79109
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UniProt
- Q9BPZ7
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Pathways
- PI3K-Akt Signaling, Fc-epsilon Receptor Signaling Pathway, Neurotrophin Signaling Pathway, Skeletal Muscle Fiber Development, CXCR4-mediated Signaling Events
Target
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