TXNIP antibody (N-Term)

Catalog No. ABIN6252540

This Rabbit Polyclonal antibody specifically detects TXNIP in WB. It exhibits reactivity toward Human.

Quick Overview for TXNIP antibody (N-Term) (ABIN6252540)

Target: TXNIP (Thioredoxin Interacting Protein (TXNIP))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TXNIP antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-TXNIP Antibody

Binding Specificity: N-Term

Purification: Protein A affinity chromatography

Immunogen: A recombinant protein fragment from the N-terminal region of human TXNIP was used as the immunogen for this antibody.

Isotype: IgG

Application Details

Application Notes: Western blot: 1-3 μg/mL

Provided assay concentrations are suggestions only, antibody titration may be required for optimal results.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: PBS with 0.1 mg/mL BSA and 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot and Store at -20C. Avoid freez-thaw cycles.

Target Details for TXNIP

Target: TXNIP (Thioredoxin Interacting Protein (TXNIP))

Alternative Name: TXNIP

Background: TXNIP (Thioredoxin-interacting protein), also called VDUP1 (Vitamin D3 upregulated protein 1) is a member of the Arrestin family of signal transduction proteins. It is a potent tumor suppressor, blocking tumor growth via blocking cell cycle progression, and reduced expression of TXNIP is found in many tumors. One way TXNIP exerts its tumor suppressive function is by suppressing NF-kB activation, possibly via regulation of the NF-kB subunit p65.

Gene ID: 10628

UniProt: Q9H3M7

Pathways: Protein targeting to Nucleus, Platelet-derived growth Factor Receptor Signaling, Inflammasome