CD14 antibody

Catalog No. ABIN6253091

This Mouse Monoclonal antibody specifically detects CD14 in FACS. It exhibits reactivity toward Human.

Quick Overview for CD14 antibody (ABIN6253091)

Target: CD14

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD14 antibody is un-conjugated

Application: Flow Cytometry (FACS)

Grade: GMP Grade

Clone: M5E2

Product Details anti-CD14 Antibody

Purpose: CD14 Unconjugated Antibody

Characteristics: The clone M5E2, a mouse monoclonal antibody, specifically recognizes a human 53-55 kDa glycosylphosphatidylinositol (GPI)-anchored single chain cell surface antigen known as CD14. The expression of CD14 is commonly observed on monocytes, interfollicular macrophages, reticular dendritic cells and some Langerhans cells. M5E2 binds with a complex of LPS and lipopolysaccharide binding protein, and blockade of CD14 with monoclonal antibodies prevented the synthesis of TNF-alpha by LPS activated leukocytes. M5E2 has crossreactivity with various species including non-human rhesus macaques.

Purification: Purified

Purity: >95 %

Immunogen: Full-length human CD14 protein

Isotype: IgG2a, kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS pH 7.2, 0.1 % (w/v) BSA, 0.09 % (w/v) sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Target Details for CD14

Target: CD14

Alternative Name: CD14

UniProt: P08571

Pathways: TLR Signaling, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades