CD21 antibody (FITC)
Quick Overview for CD21 antibody (FITC) (ABIN6253867)
Target
See all CD21 (CR2) AntibodiesReactivity
Host
Clonality
Conjugate
Application
Clone
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Specificity
- B-ly4, produces mouse IgG1 immunoglobulins directed against a 145 kD polypeptide of the human C3d receptor
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Isotype
- IgG1
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Application Notes
- immunohistochemistry on frozen tissue sections, immunohistochemistry on paraffin imbedded tissue sections
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Restrictions
- For Research Use only
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Format
- Liquid
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Storage
- 4 °C
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- CD21 (CR2) (Complement Component (3d/Epstein Barr Virus) Receptor 2 (CR2))
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Alternative Name
- CD21
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Background
- Antigen distribution: The CD21 antigen is expressed on mature B cells, follicular dendritic cells and pharyngeal and cervical epithelial cells [1,2]. CD21, also known as the Complement receptor type 2 (CR2) or Epstein-Barr virus (EBV) receptor, is a receptor for the C3 activation fragments iC3b and C3d. CD21 antibodies have been shown to bind CD23 and IFN-a. CD21 is part of a multimeric complex on B cells which includes CD19 and CD81 [3]. B-ly4 was clustered at the Leucocyte Typing Workshop IV [5].Cellular Expression: Mature B cells, follicular dendritic cells
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Pathways
- Complement System
Target
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