CD22 antibody (FITC)

Catalog No. ABIN6253872

The Mouse Monoclonal anti-CD22 antibody has been validated for FACS and ICC. It is suitable to detect CD22 in samples from Human.

Quick Overview for CD22 antibody (FITC) (ABIN6253872)

Target: CD22 (CD22 Molecule (CD22))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD22 antibody is conjugated to FITC

Application: Flow Cytometry (FACS), Immunocytochemistry (ICC)

Clone: B-ly8

Product Details anti-CD22 Antibody (FITC)

Specificity: B-ly8, produces mouse IgG1 immunoglobulins directed against human CD22, molecular weight 130-140 kD

Isotype: IgG1

Application Details

Application Notes: immunohistochemistry on cytospots, immunohistochemistry on frozen tissue sections

Restrictions: For Research Use only

Handling

Format: Liquid

Storage: 4 °C

Target Details for CD22

Target: CD22 (CD22 Molecule (CD22))

Alternative Name: CD22

Background: Antigen distribution: CD22 is detected in the cytoplasm early in B cell development (late pro-B cell stage), appears on the cell surface simultaneously with surface IgD, and is found on most mature B cells. Expression is lost with terminal differentiation of B cells and is absent on plasma cells. Activation of B cells via surface Ig increases CD22 expression [1]. CD22 reacts with most B cell leukemias including Hairy Cell Leukemia (HCL) and B cell lymphomas. Cellular Expression: Pan B cells, (surface and cytoplasmatic staining).