Afadin antibody (pSer1799)

Catalog No. ABIN6255032

This Rabbit Polyclonal antibody specifically detects Afadin in WB and IHC. It exhibits reactivity toward Human.

Quick Overview for Afadin antibody (pSer1799) (ABIN6255032)

Target: Afadin (MLLT4)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Afadin antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-Afadin Antibody

Binding Specificity: pSer1799

Specificity: Phospho-Afadin (Ser1799) Antibody detects endogenous levels of Afadin.

Cross-Reactivity: Human

Purification: The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho- and non-phospho-peptide affinity columns.

Immunogen: A synthesized peptide derived from human Afadin around the phosphorylation site of Ser1799.

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000, IHC 1:50-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline ,  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C.Stable for 12 months from date of receipt

Expiry Date: 12 months

Target Details for Afadin

Target: Afadin (MLLT4)

Alternative Name: Afadin

Background:

Description: Belongs to an adhesion system, probably together with the E-cadherin-catenin system, which plays a role in the organization of homotypic, interneuronal and heterotypic cell-cell adherens junctions (AJs). Nectin- and actin-filament-binding protein that connects nectin to the actin cytoskeleton.

Gene: AFDN

Molecular Weight: 205kDa

Gene ID: 4301

UniProt: P55196

Pathways: Cell-Cell Junction Organization