TNK1 antibody (pTyr277)

Catalog No. ABIN6256694

This Rabbit Polyclonal antibody specifically detects TNK1 in WB and IHC. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for TNK1 antibody (pTyr277) (ABIN6256694)

Target: TNK1 (Tyrosine Kinase, Non-Receptor, 1 (TNK1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TNK1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-TNK1 Antibody

Binding Specificity: pTyr277

Specificity: Phospho-TNK1 (Tyr277) Antibody detects endogenous levels of TNK1.

Cross-Reactivity: Human, Mouse (Murine), Rat (Rattus)

Purification: The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho- and non-phospho-peptide affinity columns.

Immunogen: A synthesized peptide derived from human TNK1 around the phosphorylation site of Tyr277.

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000, IHC 1:50-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline ,  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C.Stable for 12 months from date of receipt

Expiry Date: 12 months

Target Details for TNK1

Target: TNK1 (Tyrosine Kinase, Non-Receptor, 1 (TNK1))

Alternative Name: TNK1

Background:

Description: Involved in negative regulation of cell growth. Has tumor suppressor properties. Plays a negative regulatory role in the Ras-MAPK pathway. May function in signaling pathways utilized broadly during fetal development and more selectively in adult tissues and in cells of the lymphohematopoietic system. Could specifically be involved in phospholipid signal transduction.

Gene: TNK1

Molecular Weight: 72kDa

Gene ID: 8711

UniProt: Q13470