JMJD2D antibody (N-Term)

Catalog No. ABIN6256834

This anti-JMJD2D antibody is a Rabbit Polyclonal antibody detecting JMJD2D in ELISA, WB and IHC. Suitable for Human and Rat.

Quick Overview for JMJD2D antibody (N-Term) (ABIN6256834)

Target: JMJD2D (KDM4D) (Lysine (K)-Specific Demethylase 4D (KDM4D))

Reactivity: Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This JMJD2D antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-JMJD2D Antibody

Binding Specificity: N-Term

Specificity: JHD3D Antibody detects endogenous levels of total JHD3D.

Predicted Reactivity: Dog

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human JHD3D, corresponding to a region within N-terminal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Expiry Date: 12 months

Target Details for JMJD2D

Target: JMJD2D (KDM4D) (Lysine (K)-Specific Demethylase 4D (KDM4D))

Alternative Name: KDM4D

Background:

Description: Histone demethylase that specifically demethylates 'Lys-9' of histone H3, thereby playing a central role in histone code. Does not demethylate histone H3 'Lys-4', H3 'Lys-27', H3 'Lys-36' nor H4 'Lys-20'. Demethylates both di- and trimethylated H3 'Lys-9' residue, while it has no activity on monomethylated residues. Demethylation of Lys residue generates formaldehyde and succinate.

Gene: KDM4D

Molecular Weight: 52 kDa

Gene ID: 55693

UniProt: Q6B0I6

Pathways: Warburg Effect