CNGA1 antibody (Internal Region)

Catalog No. ABIN6257068

The Rabbit Polyclonal anti-CNGA1 antibody (ABIN6257068) specifically detects CNGA1 in ELISA, WB, IF and ICC. The antibody is reactive with Human, Rat and Mouse samples.

Quick Overview for CNGA1 antibody (Internal Region) (ABIN6257068)

Target: CNGA1 (Cyclic Nucleotide Gated Channel alpha 1 (CNGA1))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CNGA1 antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC)

Product Details anti-CNGA1 Antibody

Binding Specificity: Internal Region

Specificity: CNGA1 Antibody detects endogenous levels of total CNGA1.

Predicted Reactivity: Pig,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human CNGA1, corresponding to a region within the internal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for CNGA1

Target: CNGA1 (Cyclic Nucleotide Gated Channel alpha 1 (CNGA1))

Alternative Name: CNGA1

Background:

Description: Visual signal transduction is mediated by a G-protein coupled cascade using cGMP as second messenger. This protein can be activated by cyclic GMP which leads to an opening of the cation channel and thereby causing a depolarization of rod photoreceptors.

Gene: CNGA1

Molecular Weight: 79 kDa

Gene ID: 1259

UniProt: P29973

Pathways: Regulation of G-Protein Coupled Receptor Protein Signaling, Phototransduction, Asymmetric Protein Localization