IL17RC antibody (AA 680-760)

Catalog No. ABIN7215410

The Rabbit Polyclonal anti-IL17RC antibody (ABIN7215410) specifically detects IL17RC in WB and ELISA. The antibody is reactive with Human and Mouse samples.

Quick Overview for IL17RC antibody (AA 680-760) (ABIN7215410)

Target: IL17RC (Interleukin 17 Receptor C (IL17RC))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IL17RC antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-IL17RC Antibody

Binding Specificity: AA 680-760

Purpose: Rabbit Anti-IL-17RC Polyclonal Antibody

Specificity: IL-17RC Polyclonal Antibody detects endogenous levels of IL-17RC protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the C-terminal region of human IL-17RC at AA range: 680-760

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,ELISA 1:20000,Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for IL17RC

Target: IL17RC (Interleukin 17 Receptor C (IL17RC))

Alternative Name: IL-17RC

Background: IL17RC, Interleukin-17 receptor C, IL-17 receptor C, IL-17RC, Interleukin-17 receptor homolog, IL17Rhom, Interleukin-17 receptor-like protein, IL-17RL, ZcytoR14IL17RC encodes a single-pass type I membrane protein that shares similarity with the interleukin-17 receptor (IL-17RA). Unlike IL-17RA, which is predominantly expressed in hemopoietic cells, and binds with high affinity to only IL-17A, Interleukin-17 receptor C is expressed in nonhemopoietic tissues, and binds both IL-17A and IL-17F with similar affinities. The proinflammatory cytokines, IL-17A and IL-17F, have been implicated in the progression of inflammatory and autoimmune diseases. Multiple alternatively spliced transcript variants encoding different isoforms have been detected for this gene, and it has been proposed that soluble, secreted proteins lacking transmembrane and intracellular domains may function as extracellular antagonists to cytokine signaling.

Molecular Weight: 70kD

Gene ID: 84818

UniProt: Q8NAC3