ADCY2 antibody (Internal Region)

Catalog No. ABIN6257664

The Rabbit Polyclonal anti-ADCY2 antibody is suitable to detect ADCY2 in samples from Human, Mouse and Rat. It has been validated for WB, ELISA, ICC and IF.

Quick Overview for ADCY2 antibody (Internal Region) (ABIN6257664)

Target: ADCY2 (Adenylate Cyclase 2 (Brain) (ADCY2))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ADCY2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF)

Product Details anti-ADCY2 Antibody

Binding Specificity: Internal Region

Specificity: ADCY2 Antibody detects endogenous levels of total ADCY2.

Predicted Reactivity: Pig,Bovine,Horse,Sheep,Rabbit,Dog

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human ADCY2, corresponding to a region within the internal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Expiry Date: 12 months

Target Details for ADCY2

Target: ADCY2 (Adenylate Cyclase 2 (Brain) (ADCY2))

Alternative Name: ADCY2

Background:

Description: Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling (PubMed:15385642). Down-stream signaling cascades mediate changes in gene expression patterns and lead to increased IL6 production. Functions in signaling cascades downstream of the muscarinic acetylcholine receptors (By similarity).

Gene: ADCY2

Molecular Weight: 110 kDa

Gene ID: 108

UniProt: Q08462

Pathways: EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Thyroid Hormone Synthesis, cAMP Metabolic Process, Myometrial Relaxation and Contraction, G-protein mediated Events, Interaction of EGFR with phospholipase C-gamma