DECR2 antibody (Internal Region)

Catalog No. ABIN6258574

The Rabbit Polyclonal anti-DECR2 antibody (ABIN6258574) specifically detects DECR2 in WB, IF and ICC. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for DECR2 antibody (Internal Region) (ABIN6258574)

Target: DECR2 (2,4-Dienoyl CoA Reductase 2, Peroxisomal (DECR2))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DECR2 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC)

Product Details anti-DECR2 Antibody

Binding Specificity: Internal Region

Purpose: DECR2 Antibody

Specificity: DECR2 Antibody detects endogenous levels of total DECR2.

Predicted Reactivity: Pig,Zebrafish,Horse,Sheep,Dog,Chicken,Xenopus

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human DECR2, corresponding to a region within the internal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:1000, IF/ICC 1:100-1:500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for DECR2

Target: DECR2 (2,4-Dienoyl CoA Reductase 2, Peroxisomal (DECR2))

Alternative Name: DECR2

Background:

Description: Auxiliary enzyme of beta-oxidation. Participates in the degradation of unsaturated fatty enoyl-CoA esters having double bonds in both even- and odd-numbered positions in peroxisome. Catalyzes the NADP-dependent reduction of 2,4-dienoyl-CoA to yield trans-3-enoyl-CoA. Has activity towards short and medium chain 2,4-dienoyl-CoAs, but also towards 2,4,7,10,13,16,19-docosaheptaenoyl-CoA, suggesting that it does not constitute a rate limiting step in the peroxisomal degradation of docosahexaenoic acid.

Gene: DECR2

Molecular Weight: 36 kDa

Gene ID: 26063

UniProt: Q9NUI1