DECR2 antibody (AA 190-270)

Catalog No. ABIN7220956

This Rabbit Polyclonal antibody specifically detects DECR2 in WB and ELISA. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for DECR2 antibody (AA 190-270) (ABIN7220956)

Target: DECR2 (2,4-Dienoyl CoA Reductase 2, Peroxisomal (DECR2))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DECR2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-DECR2 Antibody

Binding Specificity: AA 190-270

Purpose: Rabbit Anti-DECR2 Polyclonal Antibody

Specificity: DECR2 Polyclonal Antibody detects endogenous levels of DECR2 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the C-terminal region of human DECR2 at AA range: 190-270

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,ELISA 1:10000,Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for DECR2

Target: DECR2 (2,4-Dienoyl CoA Reductase 2, Peroxisomal (DECR2))

Alternative Name: DECR2

Background: DECR2, PDCR, Peroxisomal 2, 4-dienoyl-CoA reductase, pDCR, 2,4-dienoyl-CoA reductase 2Auxiliary enzyme of beta-oxidation. Participates in the degradation of unsaturated fatty enoyl-CoA esters having double bonds in both even- and odd-numbered positions in peroxisome. Catalyzes the NADP-dependent reduction of 2,4-dienoyl-CoA to yield trans-3-enoyl-CoA. Has activity towards short and medium chain 2,4-dienoyl-CoAs, but also towards 2,4,7,10,13,16,19-docosaheptaenoyl-CoA, suggesting that it does not constitute a rate limiting step in the peroxisomal degradation of docosahexaenoic acid.

Molecular Weight: 36kD

Gene ID: 26063

UniProt: Q9NUI1