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MCF2 antibody (Internal Region)

MCF2 Reactivity: Human, Mouse WB, ELISA Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN6259504
  • Target See all MCF2 Antibodies
    MCF2 (MCF.2 Cell Line Derived Transforming Sequence (MCF2))
    Binding Specificity
    • 8
    • 8
    • 7
    • 4
    • 1
    • 1
    Internal Region
    Reactivity
    Human, Mouse
    Host
    • 28
    • 1
    Rabbit
    Clonality
    • 29
    Polyclonal
    Conjugate
    • 9
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This MCF2 antibody is un-conjugated
    Application
    • 18
    • 15
    • 14
    • 14
    • 3
    • 1
    • 1
    Western Blotting (WB), ELISA
    Specificity
    MCF2 Antibody detects endogenous levels of total MCF2.
    Predicted Reactivity
    Pig,Bovine,Horse,Sheep,Rabbit,Dog
    Purification
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogen
    A synthesized peptide derived from human MCF2, corresponding to a region within the internal amino acids.
    Isotype
    IgG
    Top Product
    Discover our top product MCF2 Primary Antibody
  • Application Notes
    WB 1:500-1:2000, ELISA(peptide) 1:20000-1:40000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Expiry Date
    12 months
  • Target
    MCF2 (MCF.2 Cell Line Derived Transforming Sequence (MCF2))
    Alternative Name
    MCF2 (MCF2 Products)
    Synonyms
    ARHGEF21 antibody, DBL antibody, MCF.2 cell line derived transforming sequence antibody, MCF2 antibody
    Background

    Description: Guanine nucleotide exchange factor (GEF) that modulates the Rho family of GTPases. Promotes the conversion of some member of the Rho family GTPase from the GDP-bound to the GTP-bound form. Isoform 1 exhibits no activity toward RHOA, RAC1 or CDC42. Isoform 2 exhibits decreased GEF activity toward CDC42. Isoform 3 exhibits a weak but significant activity toward RAC1 and CDC42. Isoform 4 exhibits significant activity toward RHOA and CDC42. The truncated DBL oncogene is active toward RHOA, RAC1 and CDC42.

    Gene: MCF2

    Molecular Weight
    108 kDa
    Gene ID
    4168
    UniProt
    P10911
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