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NEMF antibody (C-Term)

SDCCAG1 Reactivity: Human, Mouse, Rat WB, ELISA, IF, ICC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN6259616
  • Target See all NEMF (SDCCAG1) Antibodies
    NEMF (SDCCAG1) (serologically Defined Colon Cancer Antigen 1 (SDCCAG1))
    Binding Specificity
    • 16
    • 14
    • 12
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivity
    • 40
    • 28
    • 13
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Mouse, Rat
    Host
    • 54
    Rabbit
    Clonality
    • 54
    Polyclonal
    Conjugate
    • 20
    • 6
    • 4
    • 4
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This NEMF antibody is un-conjugated
    Application
    • 39
    • 30
    • 6
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
    Specificity
    SDCG1 Antibody detects endogenous levels of total SDCG1.
    Predicted Reactivity
    Pig,Bovine,Horse,Sheep,Rabbit,Dog,Xenopus
    Purification
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogen
    A synthesized peptide derived from human SDCG1, corresponding to a region within C-terminal amino acids.
    Isotype
    IgG
  • Application Notes
    WB 1:500-1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20 °C. Stable for 12 months from date of receipt.
    Expiry Date
    12 months
  • Target
    NEMF (SDCCAG1) (serologically Defined Colon Cancer Antigen 1 (SDCCAG1))
    Alternative Name
    NEMF (SDCCAG1 Products)
    Synonyms
    NY-CO-1 antibody, SDCCAG1 antibody, 1500011I12Rik antibody, 4933405E14Rik antibody, Sdccag1 antibody, nuclear export mediator factor antibody, NEMF antibody, Nemf antibody
    Background

    Description: Component of the ribosome quality control complex (RQC), a ribosome-associated complex that mediates ubiquitination and extraction of incompletely synthesized nascent chains for proteasomal degradation. NEMF is responsible for selective recognition of stalled 60S subunits by recognizing an exposed, nascent chain-conjugated tRNA moiety. NEMF is important for the stable association of LTN1 to the complex (PubMed:25578875). May indirectly play a role in nuclear export (PubMed:16103875).

    Gene: NEMF

    Molecular Weight
    123 kDa
    Gene ID
    9147
    UniProt
    O60524
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