GFER antibody (C-Term)

Catalog No. ABIN6259902

The Rabbit Polyclonal anti-GFER antibody is suitable to detect GFER in samples from Human, Mouse and Rat. It has been validated for WB and IHC.

Quick Overview for GFER antibody (C-Term) (ABIN6259902)

Target: GFER (Growth Factor, Augmenter of Liver Regeneration (GFER))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GFER antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-GFER Antibody

Binding Specificity: C-Term

Specificity: ALR Antibody detects endogenous levels of total ALR.

Predicted Reactivity: Pig,Zebrafish,Bovine,Horse,Dog,Chicken,Xenopus

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human ALR, corresponding to a region within C-terminal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000, IHC 1:50-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for GFER

Target: GFER (Growth Factor, Augmenter of Liver Regeneration (GFER))

Alternative Name: GFER

Background:

Description: Isoform 1: FAD-dependent sulfhydryl oxidase that regenerates the redox-active disulfide bonds in CHCHD4/MIA40, a chaperone essential for disulfide bond formation and protein folding in the mitochondrial intermembrane space. The reduced form of CHCHD4/MIA40 forms a transient intermolecular disulfide bridge with GFER/ERV1, resulting in regeneration of the essential disulfide bonds in CHCHD4/MIA40, while GFER/ERV1 becomes re-oxidized by donating electrons to cytochrome c or molecular oxygen.

Gene: GFER

Molecular Weight: 23-25 kDa

Gene ID: 2671

UniProt: P55789

Pathways: SARS-CoV-2 Protein Interactome