ARHGAP22 antibody (AA 540-620)

Catalog No. ABIN7223882

This Rabbit Polyclonal antibody specifically detects ARHGAP22 in WB, ELISA, IHC and IF. It exhibits reactivity toward Human and Mouse.

Quick Overview for ARHGAP22 antibody (AA 540-620) (ABIN7223882)

Target: ARHGAP22 (rho GTPase Activating Protein 22 (ARHGAP22))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ARHGAP22 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-ARHGAP22 Antibody

Binding Specificity: AA 540-620

Purpose: Rabbit Anti-ARHGAP22 Polyclonal Antibody

Specificity: ARHGAP22 Polyclonal Antibody detects endogenous levels of ARHGAP22 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the C-terminal region of human ARHGAP22 at AA range: 540-620

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,IHC 1:100-1:300,ELISA 1:40000,IF 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for ARHGAP22

Target: ARHGAP22 (rho GTPase Activating Protein 22 (ARHGAP22))

Alternative Name: ARHGAP22

Background: ARHGAP22, RHOGAP2, Rho GTPase-activating protein 22, Rho-type GTPase-activating protein 22ARHGAP22 (Rho GTPase activating protein 22) encodes a member of the GTPase activating protein family which activates a GTPase belonging to the RAS superfamily of small GTP-binding proteins. The encoded protein is insulin-responsive, is dependent on the kinase Akt and requires the Akt-dependent 14-3-3 binding protein which binds sequentially to two serine residues. The result of these interactions is regulation of cell motility. Multiple transcript variants encoding different isoforms have been found for ARHGAP22.

Molecular Weight: 77kD

Gene ID: 58504

UniProt: Q7Z5H3