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Calpain 2 antibody (N-Term)

CAPN2 Reactivity: Human, Mouse, Rat WB, ELISA, IF, ICC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN6260448
  • Target See all Calpain 2 (CAPN2) Antibodies
    Calpain 2 (CAPN2)
    Binding Specificity
    • 15
    • 11
    • 7
    • 6
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reactivity
    • 61
    • 36
    • 18
    • 5
    • 2
    • 1
    Human, Mouse, Rat
    Host
    • 60
    • 6
    Rabbit
    Clonality
    • 51
    • 15
    Polyclonal
    Conjugate
    • 29
    • 6
    • 5
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    This Calpain 2 antibody is un-conjugated
    Application
    • 41
    • 20
    • 14
    • 14
    • 14
    • 10
    • 6
    • 4
    • 3
    • 2
    • 2
    • 1
    Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
    Specificity
    Calpain 2 Antibody detects endogenous levels of total Calpain 2.
    Predicted Reactivity
    Bovine,Sheep,Chicken
    Purification
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogen
    A synthesized peptide derived from human Calpain 2, corresponding to a region within N-terminal amino acids.
    Isotype
    IgG
    Top Product
    Discover our top product CAPN2 Primary Antibody
  • Application Notes
    WB 1:1000-3000, ELISA(peptide) 1:20000-1:40000, IF/ICC 1:100-1:500
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20 °C. Stable for 12 months from date of receipt.
    Expiry Date
    12 months
  • Target
    Calpain 2 (CAPN2)
    Alternative Name
    CAPN2 (CAPN2 Products)
    Synonyms
    CANP2 antibody, CANPL2 antibody, CANPml antibody, mCANP antibody, AI326419 antibody, Capa-2 antibody, Capa2 antibody, m-calpain antibody, m-calpin antibody, capn2 antibody, CAPN2 antibody, im:6908877 antibody, zgc:109906 antibody, calpain 2 antibody, calpain 2, gene2 antibody, calpain 2, (m/II) large subunit b antibody, CAPN2 antibody, Capn2 antibody, capn2.2 antibody, capn2b antibody
    Background

    Description: Calcium-regulated non-lysosomal thiol-protease which catalyzes limited proteolysis of substrates involved in cytoskeletal remodeling and signal transduction. Proteolytically cleaves MYOC at 'Arg-226' (PubMed:17650508). Proteolytically cleaves CPEB3 following neuronal stimulation which abolishes CPEB3 translational repressor activity, leading to translation of CPEB3 target mRNAs (By similarity).

    Gene: CAPN2

    Molecular Weight
    80kDa
    Gene ID
    824
    UniProt
    P17655
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