Cathepsin D antibody (C-Term)
Quick Overview for Cathepsin D antibody (C-Term) (ABIN6260500)
Target
See all Cathepsin D (CTSD) AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- C-Term
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Specificity
- Cathepsin D Antibody detects endogenous levels of total Cathepsin D.
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Predicted Reactivity
- Pig,Bovine,Sheep,Dog
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Purification
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
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Immunogen
- A synthesized peptide derived from human Cathepsin D, corresponding to a region within C-terminal amino acids.
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Isotype
- IgG
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Application Notes
- WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- Store at -20 °C. Stable for 12 months from date of receipt.
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Expiry Date
- 12 months
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- Cathepsin D (CTSD)
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Alternative Name
- CTSD
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Background
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Description: Acid protease active in intracellular protein breakdown. Plays a role in APP processing following cleavage and activation by ADAM30 which leads to APP degradation (PubMed:27333034). Involved in the pathogenesis of several diseases such as breast cancer and possibly Alzheimer disease.
Gene: CTSD
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Molecular Weight
- 44 kDa
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Gene ID
- 1509
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UniProt
- P07339
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Pathways
- Peptide Hormone Metabolism
Target
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