CDKL5 antibody (Internal Region)

Catalog No. ABIN6260727

The Rabbit Polyclonal anti-CDKL5 antibody has been validated for WB, ELISA and IHC. It is suitable to detect CDKL5 in samples from Human and Mouse.

Quick Overview for CDKL5 antibody (Internal Region) (ABIN6260727)

Target: CDKL5 (Cyclin-Dependent Kinase-Like 5 (CDKL5))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CDKL5 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Product Details anti-CDKL5 Antibody

Binding Specificity: Internal Region

Specificity: CDKL5 Antibody detects endogenous levels of total CDKL5.

Predicted Reactivity: Pig,Bovine,Horse,Sheep,Rabbit,Dog

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human CDKL5, corresponding to a region within the internal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:1000-3000, IHC 1:200, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for CDKL5

Target: CDKL5 (Cyclin-Dependent Kinase-Like 5 (CDKL5))

Alternative Name: CDKL5

Background:

Description: Mediates phosphorylation of MECP2 (PubMed:15917271, PubMed:16935860). May regulate ciliogenesis (PubMed:29420175).

Gene: CDKL5

Molecular Weight: 116kDa

Gene ID: 6792

UniProt: O76039

Pathways: Regulation of Cell Size