CDKL5 antibody (AA 30-110)

Catalog No. ABIN7227800

This Rabbit Polyclonal antibody specifically detects CDKL5 in WB and ELISA. It exhibits reactivity toward Human and Mouse.

Quick Overview for CDKL5 antibody (AA 30-110) (ABIN7227800)

Target: CDKL5 (Cyclin-Dependent Kinase-Like 5 (CDKL5))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CDKL5 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-CDKL5 Antibody

Binding Specificity: AA 30-110

Purpose: Rabbit Anti-CDKL5 Polyclonal Antibody

Specificity: The antibody detects endogenous levels of CDKL5 protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human CDKL5 protein at AA range: 30-110

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for CDKL5

Target: CDKL5 (Cyclin-Dependent Kinase-Like 5 (CDKL5))

Alternative Name: CDKL5

Background: Cyclin-dependent kinase-like 5, Serine/threonine-protein kinase 9CDKL5 is a member of Ser/Thr protein kinase family and encodes a phosphorylated protein with protein kinase activity. Mutations in CDKL5 have been associated with X-linked infantile spasm syndrome (ISSX), also known as X-linked West syndrome, and Rett syndrome (RTT). Alternate transcriptional splice variants have been characterized.

Molecular Weight: 113kD

Gene ID: 6792

UniProt: O76039

Pathways: Regulation of Cell Size