DEFa3 antibody (Internal Region)

Catalog No. ABIN6261264

The Rabbit Polyclonal anti-DEFa3 antibody is suitable to detect DEFa3 in samples from Human and Mouse. It has been validated for WB, IHC and ELISA.

Quick Overview for DEFa3 antibody (Internal Region) (ABIN6261264)

Target: DEFa3 (Defensin, alpha 3, Neutrophil-Specific (DEFa3))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DEFa3 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Product Details anti-DEFa3 Antibody

Binding Specificity: Internal Region

Specificity: Defensin alpha3 Antibody detects endogenous levels of total Defensin alpha3.

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human Defensin alpha3, corresponding to a region within the internal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:1000-3000, IHC 1:200, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for DEFa3

Target: DEFa3 (Defensin, alpha 3, Neutrophil-Specific (DEFa3))

Alternative Name: DEFA3

Background:

Description: Defensin 2 and defensin 3 have antibiotic, fungicide and antiviral activities. Has antimicrobial activity against Gram-negative and Gram-positive bacteria. Defensins are thought to kill microbes by permeabilizing their plasma membrane.

Gene: DEFA3

Molecular Weight: 10 kDa

Gene ID: 1668

UniProt: P59666

Pathways: Cellular Response to Molecule of Bacterial Origin