Non-Syndromic Hearing Impairment Protein 5 (GSDME) (C-Term) antibody

Catalog No. ABIN6261280

The Rabbit Polyclonal anti-Non-Syndromic Hearing Impairment Protein 5 antibody (ABIN6261280) specifically detects Non-Syndromic Hearing Impairment Protein 5 in WB, IHC, IF and ICC. The antibody is reactive with Human and Mouse samples.

Quick Overview for Non-Syndromic Hearing Impairment Protein 5 (GSDME) (C-Term) antibody (ABIN6261280)

Target: Non-Syndromic Hearing Impairment Protein 5 (GSDME)

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: Un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)

Product Details

Binding Specificity: C-Term

Purpose: DFNA5/GSDME Antibody

Specificity: DFNA5/GSDME Antibody detects endogenous levels of total DFNA5/GSDME.

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human DFNA5/GSDME, corresponding to a region within C-terminal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:1000-3000, IHC 1:50-1:200 IF/ICC 1:100-1:500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details

Target: Non-Syndromic Hearing Impairment Protein 5 (GSDME)

Alternative Name: DFNA5/GSDME

Background:

Description: Plays a role in the TP53-regulated cellular response to DNA damage probably by cooperating with TP53 (PubMed:16897187, PubMed:18223688).

Gene: DFNA5

Molecular Weight: 55 kDa

Gene ID: 1687

UniProt: O60443