Endothelin 1 antibody (C-Term)

Catalog No. ABIN6261434

This Rabbit Polyclonal antibody specifically detects Endothelin 1 in WB, IHC and ELISA. It exhibits reactivity toward Human, Rat and Mouse.

Quick Overview for Endothelin 1 antibody (C-Term) (ABIN6261434)

Target: Endothelin 1 (EDN1)

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Endothelin 1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Product Details anti-Endothelin 1 Antibody

Binding Specificity: C-Term

Specificity: EDN1 Antibody detects endogenous levels of total EDN1.

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human EDN1, corresponding to a region within C-terminal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for Endothelin 1

Target: Endothelin 1 (EDN1)

Alternative Name: EDN1

Background:

Description: Endothelins are endothelium-derived vasoconstrictor peptides.

Gene: EDN1

Molecular Weight: 24kDa

Gene ID: 1906

UniProt: P05305

Pathways: Hormone Transport, Negative Regulation of Hormone Secretion, Regulation of Systemic Arterial Blood Pressure by Hormones, cAMP Metabolic Process, Regulation of Muscle Cell Differentiation, Regulation of G-Protein Coupled Receptor Protein Signaling, Regulation of Cell Size