H2AFZ antibody
Quick Overview for H2AFZ antibody (ABIN6262255)
Target
See all H2AFZ AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Specificity
- Histone H2A.Z Antibody detects endogenous levels of total Histone H2A.Z
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Cross-Reactivity
- Human, Mouse (Murine), Rat (Rattus)
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Purification
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
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Immunogen
- A synthesized peptide derived from human Histone H2A.Z
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Isotype
- IgG
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Application Notes
- WB 1:1000-3000 IHC 1:200 ICC/IF
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- Store at -20 °C.Stable for 12 months from date of receipt
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Expiry Date
- 12 months
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- H2AFZ (H2A Histone Family, Member Z (H2AFZ))
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Alternative Name
- Histone H2A.Z
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Background
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Description: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
Gene: HIST1H2AB, HIST1H2AE
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Molecular Weight
- 13kDa
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Gene ID
- 30, 128, 335
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UniProt
- P04908
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Pathways
- Telomere Maintenance
Target
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