H2AFZ antibody

Catalog No. ABIN6262255

The Rabbit Polyclonal anti-H2AFZ antibody (ABIN6262255) specifically detects H2AFZ in WB, ELISA, IHC, ICC and IF. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for H2AFZ antibody (ABIN6262255)

Target: H2AFZ (H2A Histone Family, Member Z (H2AFZ))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This H2AFZ antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF)

Product Details anti-H2AFZ Antibody

Specificity: Histone H2A.Z Antibody detects endogenous levels of total Histone H2A.Z

Cross-Reactivity: Human, Mouse (Murine), Rat (Rattus)

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human Histone H2A.Z

Isotype: IgG

Application Details

Application Notes: WB 1:1000-3000 IHC 1:200 ICC/IF

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline ,  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C.Stable for 12 months from date of receipt

Expiry Date: 12 months

Target Details for H2AFZ

Target: H2AFZ (H2A Histone Family, Member Z (H2AFZ))

Alternative Name: Histone H2A.Z

Background:

Description: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.

Gene: HIST1H2AB, HIST1H2AE

Molecular Weight: 13kDa

Gene ID: 30, 128, 335

UniProt: P04908

Pathways: Telomere Maintenance