JAG1 antibody (N-Term)

Catalog No. ABIN6262697

This Rabbit Polyclonal antibody specifically detects JAG1 in WB and ELISA. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for JAG1 antibody (N-Term) (ABIN6262697)

Target: JAG1 (Jagged 1 (JAG1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This JAG1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-JAG1 Antibody

Binding Specificity: N-Term

Specificity: JAG1 Antibody detects endogenous levels of total JAG1.

Predicted Reactivity: Pig,Bovine,Horse,Rabbit,Xenopus

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human JAG1, corresponding to a region within N-terminal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:1000-3000, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for JAG1

Target: JAG1 (Jagged 1 (JAG1))

Alternative Name: JAG1

Background:

Description: Ligand for multiple Notch receptors and involved in the mediation of Notch signaling. May be involved in cell-fate decisions during hematopoiesis. Seems to be involved in early and late stages of mammalian cardiovascular development. Inhibits myoblast differentiation (By similarity). Enhances fibroblast growth factor-induced angiogenesis (in vitro).

Gene: JAG1

Molecular Weight: 134 kDa

Gene ID: 182

UniProt: P78504

Pathways: Notch Signaling, Stem Cell Maintenance