KCNE1 antibody (Internal Region)

Catalog No. ABIN6262741

Product Details anti-KCNE1 Antibody

Target: KCNE1 (Potassium Voltage-Gated Channel, Isk-Related Family, Member 1 (KCNE1))

Binding Specificity: Internal Region

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KCNE1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)

Specificity: KCNE1 Antibody detects endogenous levels of total KCNE1.

Predicted Reactivity: Pig,Bovine,Horse,Sheep

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human KCNE1, corresponding to a region within the internal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for KCNE1

Target: KCNE1 (Potassium Voltage-Gated Channel, Isk-Related Family, Member 1 (KCNE1))

Alternative Name: KCNE1 (KCNE1 Products)

Synonyms: isk antibody, jlns antibody, mink antibody, jlns2 antibody, xkcne1 antibody, KCNE1 antibody, ISK antibody, JLNS antibody, JLNS2 antibody, LQT2/5 antibody, LQT5 antibody, MinK antibody, Isk antibody, m antibody, minK antibody, IsK antibody, nmf190 antibody, potassium channel, voltage gated subfamily E regulatory beta subunit 1 L homeolog antibody, potassium voltage-gated channel, Isk-related family, member 1 antibody, potassium voltage-gated channel subfamily E member 1 antibody, potassium voltage-gated channel subfamily E regulatory subunit 1 antibody, potassium voltage-gated channel, Isk-related subfamily, member 1 antibody, kcne1.L antibody, KCNE1 antibody, LOC474097 antibody, Kcne1 antibody

Background:

Description: Ancillary protein that assembles as a beta subunit with a voltage-gated potassium channel complex of pore-forming alpha subunits. Modulates the gating kinetics and enhances stability of the channel complex. Assembled with KCNB1 modulates the gating characteristics of the delayed rectifier voltage-dependent potassium channel KCNB1 (PubMed:19219384). Assembled with KCNQ1/KVLQT1 is proposed to form the slowly activating delayed rectifier cardiac potassium (IKs) channel. The outward current reaches its steady state only after 50 seconds. Assembled with KCNH2/HERG may modulate the rapidly activating component of the delayed rectifying potassium current in heart (IKr).

Gene: KCNE1

Molecular Weight: 15kDa

Gene ID: 3753

UniProt: P15382

Pathways: Sensory Perception of Sound