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Cytokeratin 18 antibody (C-Term)

The Rabbit Polyclonal anti-Cytokeratin 18 antibody is suitable to detect Cytokeratin 18 in samples from Human, Rat and Mouse. It has been validated for WB, IHC, IF and ICC.
Catalog No. ABIN6262779
-20% for 20 Years of ABO
$352.94
$441.17
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Quick Overview for Cytokeratin 18 antibody (C-Term) (ABIN6262779)

Target

See all Cytokeratin 18 (KRT18) Antibodies
Cytokeratin 18 (KRT18) (Keratin 18 (KRT18))

Reactivity

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Human, Rat, Mouse

Host

  • 221
  • 196
  • 3
  • 1
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Rabbit

Clonality

  • 265
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Polyclonal

Conjugate

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This Cytokeratin 18 antibody is un-conjugated

Application

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Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)
  • Binding Specificity

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    C-Term

    Purpose

    Cytokeratin 18 Antibody

    Specificity

    Cytokeratin 18 Antibody detects endogenous levels of total Cytokeratin 18.

    Predicted Reactivity

    Pig,Sheep,Rabbit

    Purification

    The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).

    Immunogen

    A synthesized peptide derived from human Cytokeratin 18, corresponding to a region within C-terminal amino acids.

    Isotype

    IgG
  • Application Notes

    WB 1:500-1:3000, IHC 1:50-1:200, IF/ICC: 1:100-1:500

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    1 mg/mL

    Buffer

    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

    Preservative

    Sodium azide

    Precaution of Use

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Storage

    -20 °C

    Storage Comment

    Store at -20 °C. Stable for 12 months from date of receipt.

    Expiry Date

    12 months
  • Target

    Cytokeratin 18 (KRT18) (Keratin 18 (KRT18))

    Alternative Name

    Cytokeratin 18

    Background

    Description: Involved in the uptake of thrombin-antithrombin complexes by hepatic cells (By similarity). When phosphorylated, plays a role in filament reorganization. Involved in the delivery of mutated CFTR to the plasma membrane. Together with KRT8, is involved in interleukin-6 (IL-6)-mediated barrier protection.

    Gene: KRT18

    Molecular Weight

    46kDa

    Gene ID

    3875

    UniProt

    P05783

    Pathways

    Apoptosis, Caspase Cascade in Apoptosis
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