M6PR antibody (Internal Region)

Catalog No. ABIN6263045

Product Details anti-M6PR Antibody

Target: M6PR (Mannose-6-Phosphate Receptor (Cation Dependent) (M6PR))

Binding Specificity: Internal Region

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This M6PR antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Specificity: M6PR Antibody detects endogenous levels of total M6PR.

Predicted Reactivity: Pig,Bovine,Horse,Sheep,Rabbit,Dog

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human M6PR, corresponding to a region within the internal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:1000-3000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for M6PR

Target: M6PR (Mannose-6-Phosphate Receptor (Cation Dependent) (M6PR))

Alternative Name: M6PR (M6PR Products)

Synonyms: CD222 antibody, CIMPR antibody, M6P-R antibody, MPR1 antibody, MPRI antibody, CD-MPR antibody, MPR 46 antibody, MPR-46 antibody, MPR46 antibody, SMPR antibody, Mpr46 antibody, CDMPR antibody, m6pr antibody, MGC68896 antibody, MGC130765 antibody, zgc:77757 antibody, wu:fj81h11 antibody, MGC89423 antibody, M6PR antibody, mprd antibody, C16orf27 antibody, GNPTAG antibody, LP2537 antibody, RJD9 antibody, insulin like growth factor 2 receptor antibody, mannose-6-phosphate receptor, cation dependent antibody, mannose-6-phosphate receptor (cation dependent) L homeolog antibody, mannose-6-phosphate receptor (cation dependent) antibody, mannose-6-phosphate receptor (cation dependent) S homeolog antibody, Cation-dependent mannose-6-phosphate receptor antibody, N-acetylglucosamine-1-phosphate transferase gamma subunit antibody, IGF2R antibody, M6PR antibody, M6pr antibody, m6pr.L antibody, m6pr antibody, m6pr.S antibody, Ethha_1678 antibody, mprd antibody, GNPTG antibody

Background:

Description: Transport of phosphorylated lysosomal enzymes from the Golgi complex and the cell surface to lysosomes. Lysosomal enzymes bearing phosphomannosyl residues bind specifically to mannose-6-phosphate receptors in the Golgi apparatus and the resulting receptor-ligand complex is transported to an acidic prelyosomal compartment where the low  pH mediates the dissociation of the complex.

Gene: M6PR

Molecular Weight: 31 kDa

Gene ID: 4074

UniProt: P20645