Melanoma Antigen Family D, 4 (MAGED4) (N-Term) antibody

Catalog No. ABIN6263074

The Rabbit Polyclonal anti-Melanoma Antigen Family D, 4 antibody (ABIN6263074) specifically detects Melanoma Antigen Family D, 4 in WB and IHC. The antibody is reactive with Human and Mouse samples.

Quick Overview for Melanoma Antigen Family D, 4 (MAGED4) (N-Term) antibody (ABIN6263074)

Target: Melanoma Antigen Family D, 4 (MAGED4)

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: Un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details

Binding Specificity: N-Term

Purpose: MAGE 1 Antibody

Specificity: MAGE 1 Antibody detects endogenous levels of total MAGE 1.

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human MAGE 1, corresponding to a region within N-terminal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:1000-3000, IHC 1:50-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details

Target: Melanoma Antigen Family D, 4 (MAGED4)

Alternative Name: MAGE 1

Background:

Description: May be involved in transcriptional regulation through interaction with SNW1 and recruiting histone deactelyase HDAC1. May inhibit notch intracellular domain (NICD) transactivation. May play a role in embryonal development and tumor transformation or aspects of tumor progression. Antigen recognized on a melanoma by autologous cytolytic T-lymphocytes.

Gene: MAGEA1

Molecular Weight: 48 kDa

Gene ID: 4100

UniProt: P43355