Melanoma Antigen Family D, 4 (MAGED4) (AA 760-840) antibody

Catalog No. ABIN7229544

The Rabbit Polyclonal anti-Melanoma Antigen Family D, 4 antibody (ABIN7229544) specifically detects Melanoma Antigen Family D, 4 in WB and ELISA. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for Melanoma Antigen Family D, 4 (MAGED4) (AA 760-840) antibody (ABIN7229544)

Target: Melanoma Antigen Family D, 4 (MAGED4)

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: Un-conjugated

Application: Western Blotting (WB), ELISA

Product Details

Binding Specificity: AA 760-840

Purpose: Rabbit Anti-MAGE1 Polyclonal Antibody

Specificity: The antibody detects endogenous levels of MAGE1 protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human MAGE1 protein at AA range: 760-840

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details

Target: Melanoma Antigen Family D, 4 (MAGED4)

Alternative Name: MAGE1

Background: Melanoma-associated antigen E1, Alpha-dystrobrevin-associated MAGE Protein, DAMAGE, Hepatocellular carcinoma-associated protein 1, MAGE-E1 antigenMAGEE encodes an alpha-dystrobrevin-associated MAGE (melanoma-associated antigen) protein, which is a member of the MAGE family. The protein contains a nuclear localization signal in the N-terminus, 30 12-amino acid repeats beginning at nt 60 with the consensus sequence ASEGPSTSVLPT, and two MAGE domains in the C-terminus. It may play a signaling role in brain, muscle, and peripheral nerve. MAGEE is located on X chromosome in a region containing loci linked to cognitive disability.

Molecular Weight: 105kD

Gene ID: 57692

UniProt: Q9HCI5