MYCNOS antibody

Catalog No. ABIN6263460

Product Details anti-MYCNOS Antibody

Target: MYCNOS (MYCN Opposite Strand/antisense RNA (MYCNOS))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MYCNOS antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Specificity: MYCNOS Antibody detects endogenous levels of total MYCNOS

Cross-Reactivity: Human

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human MYCNOS

Isotype: IgG

Application Details

Application Notes: WB 1:1000-3000 IHC 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline ,  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C.Stable for 12 months from date of receipt

Expiry Date: 12 months

Target Details for MYCNOS

Target: MYCNOS (MYCN Opposite Strand/antisense RNA (MYCNOS))

Alternative Name: MYCNOS (MYCNOS Products)

Synonyms: MYCN-AS1 antibody, NCYM antibody, NYCM antibody, MYCN opposite strand antibody, MYCNOS antibody

Background:

Description: Regulates stability of MYCN in neuroblastoma cells by inhibiting GSK3B-mediated MYCN phosphorylation. Inhibits GSK3B activity by promoting its phosphorylation at 'Ser-9' (PubMed:24391509).

Gene: MYCNOS

Molecular Weight: 12 kDa

Gene ID: 10408

UniProt: P40205