PIKFYVE antibody (N-Term)

Catalog No. ABIN6264230

Product Details anti-PIKFYVE Antibody

Target: PIKFYVE (phosphoinositide Kinase, FYVE Finger Containing (PIKFYVE))

Binding Specificity: N-Term

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PIKFYVE antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Immunohistochemistry (IHC)

Specificity: PIP5K Antibody detects endogenous levels of total PIP5K.

Predicted Reactivity: Pig,Zebrafish,Bovine,Horse,Sheep,Rabbit,Dog,Chicken

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human PIP5K, corresponding to a region within N-terminal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:1000-3000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for PIKFYVE

Target: PIKFYVE (phosphoinositide Kinase, FYVE Finger Containing (PIKFYVE))

Alternative Name: PIKFYVE (PIKFYVE Products)

Synonyms: pip5k3 antibody, wu:fo93c03 antibody, PIP5K3 antibody, fab1-like antibody, CFD antibody, FAB1 antibody, PIP5K antibody, ZFYVE29 antibody, 5230400C17Rik antibody, Pip5k antibody, Pip5k3 antibody, Pipk5k3 antibody, PipkIII antibody, p235 antibody, phosphoinositide kinase, FYVE finger containing antibody, phosphoinositide kinase, FYVE-type zinc finger containing antibody, phosphoinositide kinase, FYVE type zinc finger containing antibody, pikfyve antibody, PIKFYVE antibody, Pikfyve antibody

Background:

Description: The PI(3,5)P2 regulatory complex regulates both the synthesis and turnover of phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2). Catalyzes the phosphorylation of phosphatidylinositol 3-phosphate on the fifth hydroxyl of the myo-inositol ring, to form phosphatidylinositol 3,5-bisphosphate. Required for endocytic-vacuolar pathway and nuclear migration. Plays a role in the biogenesis of endosome carrier vesicles (ECV)/ multivesicular bodies (MVB) transport intermediates from early endosomes.

Gene: PIKFYVE

Molecular Weight: 237 kDa

Gene ID: 200576

UniProt: Q9Y2I7

Pathways: Inositol Metabolic Process