POLE2 antibody (C-Term)

Catalog No. ABIN6264335

This Rabbit Polyclonal antibody specifically detects POLE2 in WB and IHC. It exhibits reactivity toward Human and Mouse.

Quick Overview for POLE2 antibody (C-Term) (ABIN6264335)

Target: POLE2 (Polymerase (DNA Directed), epsilon 2 (p59 Subunit) (POLE2))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This POLE2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-POLE2 Antibody

Binding Specificity: C-Term

Purpose: POLE2 Antibody

Specificity: POLE2 Antibody detects endogenous levels of total POLE2.

Predicted Reactivity: Pig,Zebrafish,Bovine,Horse,Sheep,Rabbit,Chicken,Xenopus

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human POLE2, corresponding to a region within C-terminal amino acids.

Isotype: IgG

Application Details

Application Notes: IHC 1:50-1:200,WB 1:1000-3000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for POLE2

Target: POLE2 (Polymerase (DNA Directed), epsilon 2 (p59 Subunit) (POLE2))

Alternative Name: POLE2

Background:

Description: Participates in DNA repair and in chromosomal DNA replication.

Gene: POLE2

Molecular Weight: 60 kDa

Gene ID: 5427

UniProt: P56282

Pathways: Telomere Maintenance, DNA Damage Repair, Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA