Smad1/9 antibody (C-Term)

Catalog No. ABIN6265169

This Rabbit Polyclonal antibody specifically detects Smad1/9 in WB. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for Smad1/9 antibody (C-Term) (ABIN6265169)

Target: Smad1/9

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Smad1/9 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Smad1/9 Antibody

Binding Specificity: C-Term

Purpose: Smad1/9 Antibody

Specificity: Smad1/9 Antibody detects endogenous levels of Smad1/9

Predicted Reactivity: Pig,Zebrafish,Bovine,Sheep,Rabbit,Dog,Chicken,Xenopus

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human Smad1/9, corresponding to a region within C-terminal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for Smad1/9

Target: Smad1/9

Background:

Description: Transcriptional modulator activated by BMP (bone morphogenetic proteins) type 1 receptor kinase. SMAD1 is a receptor-regulated SMAD (R-SMAD). SMAD1/OAZ1/PSMB4 complex mediates the degradation of the CREBBP/EP300 repressor SNIP1. May act synergistically with SMAD4 and YY1 in bone morphogenetic protein (BMP)-mediated cardiac-specific gene expression.

Gene: SMAD1

Molecular Weight: 52kDa

Gene ID: 4086

UniProt: Q15797